SEAN O'SULLLIVAN
Managing General Partner at SOSV
· New York City Metropolitan Area, United States
Check size
$7.0M
Lead stage
pre-seed
Deals tracked
11
Sectors
Deep Tech, Climate Tech
Deep Tech
Climate Tech
Human Health
Therapeutics
Diagnostics
Biotech
pre-seed
seed
Series A
growth
United States
Global
About SEAN
Sean O'Sullivan is a Promoter at SOSV IndieBio Genesis Consortium III, L.P., a venture capital fund focused on biotech and life sciences investments. He is an active allocator with $7.0M deployed across the fund's portfolio. O'Sullivan operates within SOSV's specialized IndieBio vertical, which targets early-stage biotechnology and synthetic biology ventures
Investment thesis
Backs pre-seed deep-tech startups in biotech, human health, and planetary health through SOSV's startup studios.
SOSV is the world's most active deep tech, pre-seed venture capital firm that funds amazing deep tech founders at inception—often their very first check. Under Sean O'Sullivan's leadership as founder and Managing General Partner, SOSV backs pre-seed stage deep-tech startups across biotech, human health, and planetary health through its startup studios including HAX and IndieBio. The firm invests across pre-seed and seed stages, with a focus on founders solving critical problems in climate tech, therapeutics, diagnostics, robotics, sustainable manufacturing, and emerging technologies. SOSV deploys capital globally with offices in San Francisco, New York City, Newark, Cork, Pune, Shenzhen, and Tokyo, backing founders representing 82 nationalities across 58 countries
Investment philosophy
Sean O'Sullivan founded SOSV after his first startup went public and describes SOSV as a venture platform that supports founders at the earliest stage, with a strong emphasis on pre-seed investing through startup studios such as IndieBio and HAX. SOSV's public materials say the firm invests in companies working on human and planetary health and continues to back startups emerging from its programs with studio-led support and follow-on capital.
Investment focus
Early-stage biotech and life sciences companies. Focus on synthetic biology, biotechnology innovation, and emerging life sciences technologies through the IndieBio Genesis Consortium platform
Areas of expertise
Recent activity
Live platform data · proprietary, citable layer
Notable portfolio
Cayuga Biotech
Hoofprint Biome
Afynia
Puna Bio
Still Bright
Calder Biosciences
Hyperlume
Protonintel
Cocoon
Level Zero Health
Frequently asked
Does SEAN O'SULLLIVAN invest at pre-seed stage?
Yes. They invest at pre-seed, seed, Series A stage.
Their geographic focus includes United States, Global.
What is their typical check size?
SEAN O'SULLLIVAN's typical check size is $7.0M.
They currently invest through SOSV.
What sectors does SEAN O'SULLLIVAN focus on?
SEAN O'SULLLIVAN primarily invests in Deep Tech, Climate Tech, Human Health, Therapeutics.
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